EXPERIMENTAL TREATMENTS FOR GLIOBLASTOMA MULTIFORME (GBM)

Experimental treatments are being constantly evaluated in vitro, in animal models (Barth 1998; Barth et al, 2003; Yang et al, 2005). Some of them are already in clinical trials.

Boron neutron capture therapy (BNCT). This approach in theory allows the preferential destruction of tumor cells while sparing the normal tissue, even if the cells have microscopically spread to the surrounding normal brain (Barth and Joensuu, 2007; Yamamoto et al, 2008)

Stem Cell-based Therapy

New therapeutic approaches are being developed based on the use of stem cells as delivery vehicles or target

- Based in neural and mesenchymal stem cells (Kosztowski et al, 2009, Uchibori et al, 2009)

- As Target (Bleau et al, 2009)

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