[Radiotherapy induced glioblastoma in a child previously treated for
cerebellar medulloblastoma (case report and review of the literature)]
Pavelka Z, Brichtová E, Kren L, Skotáková J, Oltová A, Slampa P, Zitterbart K,
Stĕrba J.
Klin Onkol. 2008;21(1):31-4. Czech.
Klinika Dĕtské Onkologie LF MU Brno a FN Brno.
zpavelka@fnbrno.cz
Malignant gliomas represent the most frequent radiotherapy
induced ("secondary") solid tumor. Their prognosis remains extremely poor
despite of aggressive multimodal treatment. We present a case report of a 16
years old boy who developed cerebellar glioblastoma six years following the
combined treatment for medulloblastoma. Clinical history, pathological and
cytogenetic findings of the case are discussed along with treatment
possibilities.